Mobility and Exercise in Neurological Disorders Laboratory

Miriam King offers Dance for PD classes in the Department of Dance at Ohio State University and other locations in Franklin County. The Dance with PD classes are supported by the Movement Disorders division of Ohio State University, as well as OSU Dance.

Faculty Members

Anne Kloos, PT, PhD, NCS                   Google Scholar Link

Deb Kegelmeyer, PT, DPT, MS, GCS     Google Scholar Link

Sandra Kostyk, MD, PhD                     Google Scholar Link


Additional Videos

Our HD Exercise Program video created by the researchers in the MEND Laboratory at The Ohio State University with support from OSU Huntington's Disease Center of Excellence and the OSUMC Service Board, please click the link below

HD Exercise Program Video

Parkinson's Exercise Video

Parkinson's Exercise Video

Dr. Deb Kegelmeyer's presentation on Quantitative biomechanical assessment of trunk control in Huntington's disease reveals more impairment in static than dynamic tasks.

View Full Presentation


Research Interest/Focus

The Mobility and Exercise in Neurodegenerative Disorders (MEND) lab is primarily focused on conducting research related to assessments and interventions to measure or improve balance, mobility, and fall risk in individuals with neurodegenerative disorders. Our lab, along with collaborators, has explored the use of innovative interventions such as video game based exercise and biofeedback delivered via application software on an iPod to improve or maintain balance and gait functions in neurodegenerative populations.


Recent Graduate Students

Nora Fritz, PhD, DPT, NCS - Completed the DPT/PhD program at Ohio State from 2007-2013 and conducted her doctoral dissertation entitled "Contribution of Motor and Cognitive Factors to Gait Variability and Fall Risk: From Clinical Assessment to Neural Connectivity" in the MEND lab. Nora is completed a postdoctoral research fellowship in the Motion Analysis Laboratory at Kennedy Krieger Institute & Johns Hopkins University under the mentorship of Dr. Kathy Zackowski & Dr. Amy Bastian and is now on faculty at Wayne State University.


Location

Room 236, Atwell Hall
453 W. 10th Ave.
Columbus, OH 43210


Key Publications

Kegelmeyer DA, Kostyk SK, Fritz NE, Fiumedora MM, Chaudhari A, Palettas M, Young G, Kloos AD. Quantitative biomechanical assessment of trunk control in Huntington's disease reveals more impairment in static than dynamic tasks. Journal of the Neurological Sciences. 2017; 376:29-34

NE Fritz, DA Kegelmeyer, AD Kloos, S Linder, A Park, M Kataki, A Adeli, P Agrawal, D Scharre, SK Kostyk. Motor performance differentiates individuals with Lewy body dementia, Parkinson’s and Alzheimer’s disease. Gait & Posture. 2016;50:1-7

DW Scharre, SI Chang, HN Nagaraja, A Park, A Adeli, P Agrawal, A Kloos, DA Kegelmeyer, S Linder, N Fritz, SK Kostyk, M Kataki. Paired Studies Comparing Clinical Profiles of Lewy Body Dementia with Alzheimer’s and Parkinson’s Diseases. Journal of Alzheimer's Disease. 2016; 1-10

Kloos A, Fritz N, Kostyk S, Young G, Kegelmeyer D. Video game play (Dance Dance Revolution) as a potentialexercise therapy for Huntington's disease: a controlled clinical trial. Clin Rehabil. 2013: Vol. doi:,10.1177/0269215513487235.

Quinn,Lori; Khalil,Hanan; Dawes,Helen; Fritz,Nora,E; Kegelmeyer,Deb; Kloos,Anne,D; Gillard, Jonathan,W; Busse,Monica, Reliability and Minimal Detectable Change of Physical Performance Measures in Individuals with Pre- manifest and Manifest Huntington Disease. Physical Therapy  2013;  93: 942-956.

Fritz NE, Worstell AM, Kloos AD, Siles AB, White SE, Kegelmeyer DA. Backward walking measures aresensitive to age-related changes in mobility and balance. Gait and Posture. 2012; Nov 1, pii: S0966-6362(12)00368-2. 

Kegelmeyer DA, Parthasarathy S, Kostyk SK, White SE, Kloos AD. Assistive devices alter gait patterns in Parkinson disease: advantages of the 4-wheeled walker. Gait and Posture.2012; Vol. j.gaitpost.2012, 10.027.  

Kloos AD, Kegelmeyer DA, White SE, Kostyk SK, The impact of different types of assistive devices on gait measures and safety in Huntington's disease. PloS ONE. 2012; Vol. 7, no. 2: e30903.doi:10.1371/journal.pone.0030903.

Kloos A, Kegelmeyer D, Young G, Kostyk S. Fall risk assessment using the Tinetti Mobility Test in individualswith Huntington’s Disease. Movement Disorders.2010;  25:  2838-2844.  

Kegelmeyer DA, Kloos AD, Thomas KM, Kostyk SK. Reliability and validity of the Tinetti Mobility Test for individuals with Parkinson disease. Physical Therapy. 2007 Oct;87:1369-1378.

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